منابع مشابه
Expanding the genetic code.
Although chemists can synthesize virtually any small organic molecule, our ability to rationally manipulate the structures of proteins is quite limited, despite their involvement in virtually every life process. For most proteins, modifications are largely restricted to substitutions among the common 20 amino acids. Herein we describe recent advances that make it possible to add new building bl...
متن کاملReprogramming the genetic code.
When Maria Leptin called to say that I had been awarded the 2010 EMBO Gold Medal, I was delighted and surprised. The roll call of past winners is impressive, and I had been at the Laboratory of Molecular Biology (LMB) when Jan Löwe had received the award in 2007 for his elegant work on the bacterial cytoskeleton (Michie and Löwe, 2006). I also knew that several other LMB scientists, including B...
متن کاملThe genetic code.
After the double-helical structure of DNA was revealed in 1953, researchers had before them the chance to unlock an utterly compelling puzzle, one for the ages and fundamental to the processes of life: What code linked DNA sequences to each of the 20 amino acids that comprised proteins? Every biology textbook now lists which three RNA bases correspond to which amino acid, but in 1961, that was ...
متن کاملThe Genetic Code
In this paper I will review the genetic code. An overview of its functions and inner workings will be given. Also the current theories on the origin and emergence of the canonical genetic code from early codes will be explored.
متن کاملCrystalizing the genetic code.
New developments are presented in the framework of the model introduced bythe authors in References [1, 2] and in which nucleotides as well ascodons are classified in crystal bases of the quantum group U(q)(sl(2) ⊕ sl (2)) in the limit q → 0. An operator whichgives the correspondence between the amino-acids and the codons isobtained for any known genetic code. The free energy released by basepa...
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ژورنال
عنوان ژورنال: Artificial DNA: PNA & XNA
سال: 2014
ISSN: 1949-095X,1949-0968
DOI: 10.4161/adna.29408